Origins of Life: A work in progress (Slides from a lecture by Andrew Pohorille at Stanford University, April 2000.)

1 The Famous Miller Experiment	2 Metabolic Pathways Permission to use this image granted by Pathway Solutions Inc. Credit: Kanehisa Laboratories	3 Rubisco
4 Continuity Hypothesis	5 Conditions on the Early Earth	6 History of the Earth
7 Chemical Evolution	8 Meteorite Impacts	9 Sources of Organic Carbon
10 Atmosphere of the Early Earth	11 Composition of the Prebiotic Atmosphere	12 Meteoritic Organic Compounds (Thanks to George Cooper)
13 Interstellar Organic Compounds (Thanks to Max Bernstein)	14 Prebiotic Metabolic Pathways (Thanks to Art Weber)	15 Protocells...
16 Organics to Cells	17 Emergence of Cells	18 Progression to a protocell
19 Minimal functioning protocell	20 The Problem...	21 The Central Dogma
22 The DNA double-helix	23 Components of RNA	24 Replication of Nonenzymatic RNA
25 Selection of Catalytic RNA	26 Critique of the RNA World	27 Simple Proton Pump
28 Bacteriorhodopsin in a Membrane	29 Proton Transport in BR	30 Light Driven Synthesis of ATP
31 Collective Properties	32 Contacting Andrew pohorill@raphael.arc.nasa.gov	The End